Solution-Did the researchers follow the scientific method | Free AI Content | Essay Helper
Trace the Scientific Method in a Primary Research Scientific Article
AIDresses course outcomes 1 and 4:
use knowledge of biological principles and the scientific method to ask and answer relevant questions about the human body
weigh and make health-related decisions based on an understanding of the value and limits of scientific knowledge and the scientific method
Before attempting this assignment, you might want to revisit the Scientific Method Tutorial in the Science Learning Center under the Course Content area.
Substance in Green Tea Inhibits Inflammatory Breast Cancer Cells
Inflammatory breast cancer (IBC) is a rare and often fatal form of breast cancer. In IBC, lymphatic vessels in the skin are blocked causing the breasts to appear swollen and red. Early in the disease process, patients with IBC usually do not have the classic “lump” in their breast; therefore the disease is frequently diagnosed at later stages. Diagnosis is often so delayed that the cancer has metastasized and patient prognosis is poor.
The underlying cause of IBC is unknown, but it is believed that like with other cancers cetain cell types have the abililty to transform into cells that can form malignant tumors. These aberrant cells are considered cancer stem cells, and populations of cancer stem cells have been identified in IBC.
In a recent, study researchers evaluated whether a metabolite found in green tea could inhibit the growth of certain stem cell types that have been identified in the breast tissue of patients with IBC. In this study, two IBC stem cell types, SUM-149 and SUM-190, were exposed epigallocatechin-3-gallate (EGCG- is a potent antioxidant found in green tea). Results from the study showed that EGCG treatment inhibited the growth, spread, and survival of the two stem cell types.
For the following questions, please refer to the original paper. The link to the paper is: http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0073464&representation=PDF
What is the overall hypothesis of this experiment? (Reminder: a hypothesis is a statement that can be tested).
In the Materials and Methods section of the paper, the authors discuss the cell culture and treatment conditions. What was the control group treated with in this section (make sure to look only at the Cell Culture and Treatment section of the paper)? Why?
Again, looking only at the Cell Culture and Treatment section, what was the experimental group treated with? Why?
In the Results section of the paper, the authors clearly summary their multiple findings. In the “EGCG Reduces Growth of Pre-existing Tumors Derived from SUM-149 Stem-like Cells” results sub-section, the authors report a specfic finding. What specific result do the researchers report?
Did the researchers follow the scientific method in their experimental design? Explain.
Based on the results, was the hypothesis supported, and what can you conclude from this experiment?
Mineva et al. (2013). Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells. PLoS ONE, 8(9): e73464. Doi:10.1371/journal.pone.0073464
We've got everything to become your favourite writing service
Money back guarantee
Your money is safe. Even if we fail to satisfy your expectations on your paper, our money back guarantee allows you to request a refund.
Confidentiality
We don’t our clients private information with anyone. What happens on our website remains confidential.
Our service is legit
We always keep our word and follow every instruction on order, and this kind of academic assistance is perfectly legitimate.
Get a plagiarism-free paper
We check every paper for plagiarism before submission, so you get a unique paper written for your particular purposes.
We can help with urgent tasks
Need a paper tomorrow? We can write it even while you’re sleeping. Place an order now and get your paper in 4 hours.
Pay a fair price
Our prices depend on urgency of your paper. If you want a cheap essay, place your order in advance. Our prices start from $11 per page.